Posted by: Dan | February 20, 2007

A Link Between Obesity and Malnutrition

For an interesting post on the role of leucine (an essential amino acid) in metabolism, check out Isabella Mori’s Change Therapy. In particular, researchers at Penn State have uncovered a molecular switch that responds to changing levels of leucine in the diet, and may be involved in shifting metabolic responses. Isabella notes that this research is relevant to not just obesity, but also malnutrition and the starvation response – and so the protein, GCN2 eIF2alpha kinase, may be a potential drug target – but there are caveats as well.

Read on at Change Therapy.


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