Briefly, Nature has a supplement on the state of signaling in cancer, with an editorial and six reviews:
Thirty years of oncogene research have provided fascinating insights into the molecular basis of cancer. Many hurdles remain in the race to beat cancer, but as the articles in this Insight show, a growing understanding of the complex signalling pathways that underlie tumour formation and progression is driving the development of a new generation of anticancer drugs targeted at specific molecular events.
Included in the reviews is one by Gerhard Christofori, New signals from the invasive front.”
- Insight: Signalling in cancer. Nature. 441(7092):423-457. Nature Publishing Group.